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Change of the Shape.
Fig. 1 Virus-induced consecutive stages of deformation of rhesus monkey erythrocytes(a, b, c)
a – control sample. Deformations were caused by cell-to-cell interaction;
b - rhesus monkey erythrocytes after interaction with influenza virus;
c – final degradation of rhesus monkey erythrocytes after 90 minute interaction with canine parvovirus.
Changes of the shape of RBC are polymorphous and depend on the nature of action. Deformation associated with cell-virus interaction depended on the family of viruses and the source of erythrocytes. For example, some viruses interact with of rhesus monkey erythrocytes and are neutral to goose and chicken erythrocytes and vice versa.
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Fig. 2 These scans show the shape of chicken erythrocytes before (a) and after (b) interaction with rubella virus.
Changes of the shape of RBC arise also after mechanical deformation [5] and chemical action [6,7]. Biochemical causes of these changes are not clear yet [8].
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