Closed liquid cell with heater and temperature sensor which provides flow-through possibility and heating (up to 60C, stability ~0,05C) enables control and changing of the biochemical environment in solution during measurements. For biological applications. Range of sample positioning 1x1 mm (limited by membrane), positioning resolution 5 um. For heads (SFC050LNTF, SFC100LNTF) on SCC01NTF. Chemicaly stable materials of liquid cell (stainless steell, fluoroplast) allow to operate in agressive liquids such as solvents of H2SO4, HCl.