Virus-cell Interaction

Virus-cell Interaction.

Virus-cell interaction can be considered as an example of special action on the membrane. This is a more complex process than chemical or mechanical action. Its results depend on the family of viruses and the source of erythrocytes. Moreover, the virus-erythrocyte reaction can differ for two different strains of the same virus. Virus-erythrocyte interaction changes the fine structure of the membrane and the shape of red blood cells. We can observe viral particles on the membrane surface when virus-erythrocyte interaction is lacking and there is only sorption process. Virus-erythrocyte interaction is described in [4]. Samples were prepared by cell sedimentation from a suspension (see Suspension. Overall View). The intermittent contact mode was used. Two signals were determined simultaneously. The latter signal corresponded to the ERROR MODE. It was used to localize fine features that corresponded to defects on the membrane or adsorbed viral particles (10-20 nm) against the background of sharp changes of height associated with the shape of RBC (difference about 1 micron).